• Because suicide systems can be designed

  2018-11-08

  

  Because suicide systems can be designed not to evoke cross-resistance to conventional agents, they can potentiate therapy—efficiently inducing apoptosis in transduced cells—without increasing toxicity. However, many suicide systems have drawbacks, proving less clinically effective than desired. HSV-

• br Experimental Procedures br Author Contributions

  2018-11-08

  

  Experimental Procedures Author Contributions Acknowledgments Introduction MicroRNAs (miRNAs) are short, endogenous, non-coding RNAs that repress gene expression post-transcriptionally by destabilizing and/or repressing translation of target mRNAs. In the canonical biogenesis pathway, pri

• Neurogenesis in the adult mammalian brain

  2018-11-08

  

  Neurogenesis in the adult mammalian lxr agonists occurs throughout life and has been clearly demonstrated at two locations under physiological conditions: the SVZ of the lateral ventricle and the subgranular zone (SGZ) of the DG in the hippocampus (Alvarez-Buylla and Lim, 2004). Several studies hav

• EWS FLI a widely recognized fusion oncogene for Ewing

  2018-11-08

  

  EWS-FLI1, a widely recognized fusion oncogene for Ewing sarcomas, is generated by the chromosomal translocation of t(11;22) (q24;q12), which consists of the N-terminal transactivator domain of the EWS gene and the C-terminal ETS DNA binding domain of the FLI1 gene. The resulting EWS-FLI1 fusion prot

• br Results br Discussion In the present study we

  2018-11-08

  

  Results Discussion In the present study we show that LPA1 is expressed by stem and progenitor histone deacetylase inhibitors (predominantly type 1 and type 2a) within the neurogenic niche of the dentate gyrus of adult mice, and that it outperforms Nestin, the current gold standard, as a marker

• br Experimental Procedures See Supplemental Experimental Pro

  2018-11-08

  

  Experimental Procedures See Supplemental Experimental Procedures for details on mice, flow cytometry and cell sorting, cell-cycle and apoptosis analysis, myeloid progenitor and Lys-GFP in vitro differentiation assay, and gene expression. Author Contributions Acknowledgments Introduction

• Despite the importance of bridging social capital

  2018-11-07

  

  Despite the importance of bridging social capital, there is an important gap in the literature related to its measurement. Only a few studies have measured this simvastin concept in the public health literature (Barman-Adhikari & Rice, 2014; Enfield & Nathaniel, 2013; Maselko, Hughes, & Cheney, 201

• The observed protective effect of spatial access

  2018-11-07

  

  The observed protective effect of spatial access to temples on adolescent continued alcohol use could be explained by the collective process of religion. Traditional temples are usually located in historical urban areas and reflect the retention of a territorial sense of place and local identity in

• This ability of algae to remove heavy metals varies with

  2018-11-07

  

  This ability of algae to remove heavy metals varies with the different strains of algae and it is generally in the following green algae descending order Chlorophyta – Phaeophyta (red algae) Rhodophyta (Al-Shwafi and Rushdi, 2008). Furthermore, it was found that the lifeless algae buy GLPG0634 adsor

• Missio and Jayme the basic hypothesis is that maintaining

  2018-11-07

  

  Missio and Jayme (2012), the basic hypothesis is that maintaining a competitive exchange rate induces investment and structural change in the economy. By enabling changes in the outcome structure, the exchange is able to influence the long-run supply, especially in exports-related business. The auth

• order buspirone hcl Some studies have shown improvement in

  2018-11-07

  

  Some studies have shown improvement in insomnia following an anti-stress massage [22,23]. It has also been reported that women experiencing insomnia as a symptom of menopause tend to select alternative therapies, particularly body therapies, as their first choice of therapy [24]. In a recent pilot s

• In our study those participants with the

  2018-11-07

  

  In our study, those participants with the highest genetic risk score of 6 had an increased risk for EFV discontinuation compared to those participants with risk scores 1–5. We therefore performed a post hoc analysis of pooled data of 781 patients starting EFV-based regimens from our cohort and the p

• Remarkably Cornelius et al report for the first time

  2018-11-07

  

  Remarkably, Cornelius et al. report for the first time HBV-neutralizing antibodies in all seven so-far tested human recipients of the BM32 vaccine, i.e., of preS antigen without other HBV antigens. Assay of neutralizing antibodies has been difficult because for long time the only HBV-susceptible cel

• The in vivo replication kinetics of ZIKV

  2018-11-07

  

  The in vivo replication kinetics of ZIKV in natural human infections remains elusive. The neurotropic nature of ZIKV has been evidenced by mouse experiments (Cugola et al., 2016) and clinical investigations (Carteaux et al., 2016). Our necropsy data from two animals demonstrate that the contemporary

• miR a and miR b are two miRNAs of the

  2018-11-07

  

  miR-146a and miR-146b are two miRNAs of the same family that share the same seed sequence and only differ by two nucleotides at the 3′ end in their mature sequences. However, they are encoded by distinct genes located on separate chromosomes, which implies that they may fulfil distinct functions. In

15363 records 1007/1025 page Previous Next First page 上5页 10061007100810091010 下5页 Last page