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br Materials and Methods br Results br
2018-11-07
Materials and Methods Results Discussion In our study, we were surprised to find that the transmission is limited to F1 generation. One possible explanation for the limited transmission for enhancement of LTP is that the phenotype ends at a younger age in the offspring of FSs rats than in t
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br Materials and Methods br Results br
2018-11-07
Materials and Methods Results Discussion The intellectual ability testing tool we used, C-WISC, is the Chinese version of WISC-III. It is widely used for intellectual assessment for children from 3 to 7 (Moura et al., 2014). The main parameters of the C-WISC (VIQ, PIQ, and FIQ) represent th
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br Search Strategy and Selection Criteria
2018-11-07
Search Strategy and Selection Criteria Conflicts of Interest Acknowledgments Introduction Chronological age is a major risk factor for functional impairments, chronic diseases and mortality. However, there is still great heterogeneity in the health outcomes of older individuals (Lowsky e
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Since IM oxytocin reaches its site
2018-11-07
Since IM oxytocin reaches its site of action, the uterus, via the plasma it is proposed that demonstrating a comparable plasma drug profile following IH and IM routes of administration allows for extrapolation from the extensive clinical safety and efficacy data for the approved IM oxytocin product
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We then went on to
2018-11-07
We then went on to see if these proteins bound non-specifically to an p2x7 of affinity resins; FLAG, TALON, Calmodulin and IgG and identified hundreds of non-specific interactors for each resin. We compared these lists to identify which proteins bind to multiple resins non-specifically. We refer to
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br Data Here we described the synergistic
2018-11-07
Data Here, we described the synergistic anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with the doxorubicin hydrochloride treatment in mice. The combinatorial effects of Selaginella tamariscina extract (Fig. 1A) or amentoflavone (Fig. 1B) on the anti-tumor action
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br Identification of needs br Example
2018-11-07
Identification of needs Example applications Design requirements Design In this section, we discuss the preliminary design of the proposed Mezuri platform architecture aimed at addressing the above derived engineering requirements. For the sake of expediency, the first prototype of the M
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beta-lactamase One of the more critical contextual influence
2018-11-07
One of the more critical contextual influences at hand is the availability and prevalence of substances of abuse, increasing the likelihood that individuals will select substance use as a risk behavior of choice. For example, in the United States, by age 18, 75.6% of adolescents have used alcohol, 4
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purchase ABT-888 An important feature of social behavior in
2018-11-07
An important feature of social behavior in each of these phases is that within phase social engagement is highly motivated. Individuals will energetically seek out the developmentally appropriate form of social behavior and they will experience distress when this target is impeded. Highly motivated
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Power in the delta frequency band of the EEG
2018-11-07
Power in the delta frequency band of the EEG is the predominant frequency in early life as neural activity develops into its adult-like form (Bell, 1998; Stern et al., 2001). Delta oscillations are visible in primitive animal brains (González et al., 1999) and, in humans, have been linked to generat
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The DA system undergoes significant reorganization over adol
2018-11-07
The DA system undergoes significant reorganization over adolescence, which is implicated in the pathophysiology of various disorders that appear during adolescence (see Nelson et al., 2005; Spear, 2000; Wahlstrom et al., 2010a). Across rodents, non-human primates, and humans, increases in dopamine
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Evidence that further clarifies the
2018-11-07
Evidence that further clarifies the deficient regulation of emotional reactivity by prefrontal control regions in MDD comes from studies of task-based functional connectivity (FC). Rather than examining which regions are more active in one task than another, FC examines the correlation of activity b
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Given the increased vulnerability for
2018-11-07
Given the increased vulnerability for anxiety among individuals with BI through the moderating role of attention bias, the present study aims to examine the BI-attention-anxiety link by delineating the electrophysiological correlates of threat bias in an at-risk sample. The dot-probe task, a standar
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We used a mixed model ANOVA to evaluate whether the
2018-11-07
We used a mixed-model ANOVA to evaluate whether the ERPs of the selective attention effect varied as a function of 5-HTTLPR. The ANOVA included the between-group factor of three 5-HTTLPR genotypes (long-long, short-long, and short-short), and the within-group factor of three levels of electrode loca
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Neuroimaging studies also provided evidence for a dissociati
2018-11-07
Neuroimaging studies also provided evidence for a dissociation between lexical/grammatical processing and sound-based paricalcitol to time compressed speech, the two processes involving different neural pathways. In an fMRI study, Peelle et al. (2004) presented syntactically simple or complex senten
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