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O processo de sele o
2019-04-22
O processo de seleção é crucial, pois ubiquitin e3 ligase ‘escolhida’ será a responsável, nos próximos cinco anos, pela gestão do hospital determinado, decisão publicada em Diário Oficial. Dois aspectos são merecedores de atenção. Inicialmente, a decisão unilateral de escolha pelo Secretário de Saúd
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Cy5.5 NHS ester manufacturer Adequate nutritional support fo
2019-04-22
Adequate nutritional support for pregnant women is an important issue, not only to help such women maintain peak health and performance, but also as it indirectly affects fetal growth and the minimization of adverse fetal outcome risks. Among those nutritional components that are integral to this su
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In an earlier study we
2019-04-20
In an earlier study, we used a questionnaire to assess musculoskeletal pain in patients with CML who had achieved DMR (MR4.0) and discontinued TKI treatment, including IM, nilotinib, and dasatinib [5]. Nine out of the 27 patients surveyed developed musculoskeletal pain after discontinuing TKIs. In t
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gingerol Desde esta ptica Jim nez opina que el
2019-04-20
Desde esta óptica, Jiménez opina que el , como pocos artistas de su momento, “sabía que el país se encontraba tironeado entre los afanes de modernización política y cultural de sus élites y el rezago económico y social de su inmensa mayoría”, panorama nada ajeno gingerol más de un siglo de distancia
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br Discussion HIV testing and linkage to
2019-04-20
Discussion HIV testing and linkage to care are essential for fighting the HIV epidemic, and evidence-based methods for increasing coverage of testing and accelerating linkage to care are needed. We report that abbreviated counselling was as effective as full length counselling in reducing sexual
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Real time quantitative polymerase chain reaction
2019-04-20
Real-time quantitative polymerase chain reaction (RQ-PCR) was performed to quantify BCR/ABL1 transcript as described previously [1]. The quantitative results were expressed as percent ratios relative to an ABL1 internal control using the following formula (p210 BCR–ABL/ABL1×100×CF) [2]. The level of
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Regarding the expression of NKp
2019-04-20
Regarding the expression of NKp46/NCR1 (Fig. 1A and B), both increased and decreased expression are observed depending on patients. Interestingly, the expression of the inducible molecule NKp44/NCR2 is clearly induced in 3 patients (PT1, PT2 and PT5) both regarding the percentage and the MFI. In con
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br Conclusion br Introduction Multiple
2019-04-20
Conclusion Introduction Multiple myeloma is a malignant plasma cell disorder, comprising approximately 10% of all haematological malignancies, and its incidence is increasing [1]. The pathogenesis is complex, culminating in malignant transformation of clonal plasma cells. The aetiology is not
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GSK503 India is the second largest consumer and third
2019-04-20
India is the second largest consumer and third largest producer of tobacco in the world. The Indian Government has been significantly engaged in addressing the tobacco problem. A major policy, the Cigarettes and Other Tobacco Products Act (COTPA) was implemented in 2003, followed by WHO\'s Framework
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azilsartan medoxomil ZIKV is a flavivirus related to dengue
2019-04-19
ZIKV is a flavivirus related to dengue virus (DENV) and historically has been transmitted by the same mosquito species, (). There is no available treatment or vaccine so disease control is limited to the management of mosquitoes which currently relies on either insecticides or the destruction of la
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br We sincerely appreciate the comment
2019-04-19
We sincerely appreciate the comment by Lombardi et al on our published paper. demonstrates the incidence of dyspnea and the discontinuation of ticagrelor due to dyspnea in patients who reported dyspnea in Phase 3/4 clinical trials of acute coronary syndrome with available relevant data. Our study
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Since antithrombotic therapy for patients
2019-04-19
Since antithrombotic therapy for patients with AF is rapidly changing with the increasing use of dabigatran, rivaroxaban, and apixaban, some of the primary issues that will influence the future revision of various guidelines (HRS [Heart Rhythm Society], ESC [European Society of Cardiology], ACC [Ame
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br Discussion br Conflict of
2019-04-19
Discussion Conflict of interest Introduction Device implantations may be challenging in patients with venous abnormalities. The most common congenital variation, frequently associated with other congenital abnormalities, is a persistent left superior vena cava (PLSVC), and successful atrial
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Efforts to estimate the global burden of
2019-04-19
Efforts to estimate the global burden of typhoid fever can be traced to a meeting of the Pan American Health Organization in 1984 and publication of the outcome in 1986. Although an important first step, the 1984 study was recognised as having a number of limitations including provision of scanty me
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GSK343 What would mitigation strategies to deal with
2019-04-19
What would mitigation strategies to deal with future pandemic risks of zoonotic disease look like? Analyses of emerging disease trends during the past six decades have shown that Ebola fits the GSK343 pattern. This pattern involves zoonotic spillover from wildlife or livestock driven by changes in
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