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br Materials and methods br Results
2022-01-17

Materials and methods Results Discussion Genetic analyses conducted here were based on specific features of PhyChem indexes for nt dimers extracted to generate a numerical sequence representation, which was used to build models for distinguishing HVR1 variants between CIP and MIP. This data
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Table shows the distribution of all studied groups
2022-01-17

Table 3 shows the distribution of all studied groups regarding mutation of GSTP1 gene polymorphism in each group. From 15 COPD smoker patients in group (A), 12 (80%) had heterozygous mutation, from 15 COPD non-smoker patients in group (B), 5 (33.3%) had heterozygous mutation, from 10 control subject
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The average pregnancy rate in this work
2022-01-17

The average pregnancy rate in this work was 60.1%; similar results have been reported with the same estrus synchronization treatment (58% pregnancy rate) [26]. Later studies also showed that the pregnancy rate was 56.9 and 51.1%, with FTAI and estrous detection, respectively [34,35]. Although that t
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BHQ The current study also inferred that MT content
2022-01-17

The current study also inferred that MT content in Crassostrea gigas might be associated with the Cd level, and can be affected by MT turnover. The BHQ of MT in cytosol is beneficial for aquatic organisms to adapt the seawater contaminated by heavy metals, and MT is a biomarker for marine invertebr
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Glutamate is a ubiquitous principal excitatory neurotransmit
2022-01-17

Glutamate is a ubiquitous principal excitatory neurotransmitter in the gamma secretase inhibitor that plays a central role in a variety of brain functions (Delgado, 2013, Hawkins, 2009). Several studies reported that CSF glutamate was associated with mental illness, including major depressive disord
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Next we focused on B part the phthalazine ring
2022-01-17

Next, we focused on B-part, the phthalazine ring. While both nitrogen atoms of the phthalazine ring were found to be important (data not shown), replacing the benzene ring of the phthalazine part was attempted, and shows the results of the substituted pyridazine rings with bearing 2-methoxy benzene
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Amongst oxidants that we have studied
2022-01-17

Amongst oxidants that we have studied, PMS is unique in having a greater effect in deoxygenated cells. The resulting phenotype shows some similarities with the increased cation permeability shown by deoxygenated sickle RN 1734 [27]. It is interesting to consider why PMS has this effect. PMS function
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Isolation and application of cold adapted galactosidase in t
2022-01-17

Isolation and application of cold-adapted β-galactosidase in the production of low lactose dairy products would play a critical role in improving access to low lactose dairy products for lactose intolerant individuals [9,11]. Milk contains high levels of K+, Ca2+, and Na+, and β-galactosidase used i
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The extensive worldwide research efforts in
2022-01-17

The extensive worldwide research efforts in the decade following FFA1 de-orphaning aimed at developing clinically useful FFA1 agonists were nearly halted after Takeda’s first-in-class agent fasiglifam (TAK-875) was discontinued in phase III of human trials. On the date of submission of this manuscri
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Recent research has focused on identifying key agonists and
2022-01-17

Recent research has focused on identifying key agonists and receptors mediating nutrient-induced GLP-1 and insulin secretion. The long-chain fatty p-Cresyl sulfate receptor GPR40 is the most abundant GPCR expressed in islet β cells and is also expressed on intestinal L-cells, where it contributes to
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br Experimental procedures br Results br Discussion This
2022-01-15

Experimental procedures Results Discussion This study demonstrates that the genetic disruption or pharmacological inhibition of FAAH completely prevented all manifestations of pain symptoms in an NTG-induced migraine animal model. Thus, FAAH disruption or blockade abolished the activation o
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peptide yy sale In the Hedgehog signaling pathway cholestero
2022-01-15

In the Hedgehog signaling pathway, cholesterol is required to activate SMO (Cooper et al., 2003), the downstream target of PTCH1. A previous study (Bidet et al., 2011) reported that Patched expression in yeast peptide yy sale increased extrusion of a fluorescent boron dipyromethanene sterol derivati
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The inhibition of HDAC increases
2022-01-15

The inhibition of HDAC increases the level of histone acetylation and consequently turns the chromatin to be loose and active, allowing multiple transcription factors to access to promoters of diverse genes including tumor suppressor genes []. As compound possessed potent HDAC inhibitory activity a
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Electrostatic potential along with measurement and modeling
2022-01-15

Electrostatic potential along with measurement and modeling of corresponding energies is vital for inferring protein properties, lone or complexed with ligands. DelPhi was used for solving Poisson Boltzmann equation, obtaining grid, total reaction and coulombic energies after solvating the proteins
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Hesperidin is an abundant and inexpensive plant flavonoid la
2022-01-15

Hesperidin is an abundant and inexpensive plant flavonoid, largely derived from citrus species including sweet orange and lemon. Hesperetin (Hst) is the aglycone of hesperidin. Hesperidin and hesperetin have been reported to show a battery of pharmacological properties, including anti-hyperlipidemic
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