• ClC is a member of the voltage gated chloride channel

  2020-04-17

  

  ClC-3 is a member of the voltage-gated chloride channel superfamily and has many roles in cell proliferation, apoptosis, kinase inhibitors progression and so on (Dai et al., 2005). A growing number of studies showed that ClC-3 encoded a volume-regulated Cl− channel (ICl,Vol) in heart, that could con

• Kinetic isotope effects KIEs inform on bond

  2020-04-17

  

  Kinetic isotope effects (KIEs) inform on bond vibrational changes between the ground state (GS) and TS of a chemical reaction and remain one of the most powerful experimental techniques for interrogating TS structure. KIEs on enzyme reactions measured by the internal Cy5 maleimide (non-sulfonated)

• Recoverin is a kDa retinal protein

  2020-04-16

  

  Recoverin is a 23-kDa retinal protein that binds to calcium. It regulates the Doxofylline of rhodopsin during visual transduction within photoreceptor cells. Since the pathogenicity of anti-recoverin antibody is potent, anti-recoverin CAR patients often have progressive visual impairments, characte

• CDK S phosphorylation status influences the differential cel

  2020-04-16

  

  CDK5-S47 phosphorylation status influences the differential cellular proliferation versus migration response: Previous work from our laboratory has shown CDK5 to be a critical determinant of the cellular proliferation-migration dichotomy whereby CDK5 activation downstream of stimulated epidermal gro

• br Materials and methods br Results The monoclonal antibody

  2020-04-16

  

  Materials and methods Results The monoclonal antibody (mAb), 12G5, reacts specifically with the human fusin protein and recognizes the protein on many T-cell lines such as the SUP-T1 ursolic acid (Endres et al., 1996). As shown in Fig. 1, AMD3100 at 25 μg/ml completely inhibited the binding of

• br Discussion Immune response to CMV

  2020-04-16

  

  Discussion Immune response to CMV is a series cell-mediated immune response initiated by innate innate NK cells, followed by adaptive CD8+ and CD4+ T cells and humoral immunity by B cell [3]. Prior to transplant, measurement of humoral immune responses (CMV serology) of donor and recipient is com

• We further verified the presence of

  2020-04-16

  

  We further verified the presence of CLIC1, CLIC4 and CLIC5 in purified mitochondria following protocols described earlier (Singh et al., 2012). As shown in Fig. 4, CLIC4 and CLIC5 were present in the ultra-pure mitochondrial fraction (M3). All the three fractions obtained from 30% (v/v) Percoll grad

• Capecitabine br Materials and methods br Data and statistica

  2020-04-16

  

  Materials and methods Data and statistical analysis The results were expressed as mean ± SEM. One-way analysis of variance (ANOVA), followed by Bonferroni\'s post-test or unpaired Student\'s t-test were used to determine significant differences between groups. The program used for statistical

• Oxytocin receptor Asteroids can provide an abundant supply o

  2020-04-16

  

  Asteroids can provide an abundant supply of other resources, such as carbon, nitrogen, or calcium compounds, but will only be useful once the space economy is sufficiently developed to provide economically interesting uses for them. Others, such as titanium or aluminium, also exist in asteroids, but

• The first group of tests

  2020-04-16

  

  The first group of tests was intended to evaluate the performance of the GUI initialization. We evaluated the times obtained for different initial GUI models with 1, 2, 3, 5, 10, and 20 components as shown to the user. These sizes were chosen since GUIs (developed within our COTS-based architectures

• Our module is designed to allow in process

  2020-04-16

  

  Our module is designed to allow in-process measurement of [C]-tracer molar activity (MA, GBq/μmol at EOB) using a Okadaic acid australia detector with a UV detector at the outlet of the HPLC-portion of the system. In the HPLC chromatogram, peak analysis of the chromatographic data utilized PeakSimp

• This study focused on NPC L because it is

  2020-04-16

  

  This study focused on NPC1L1 because it is critical for intestinal Pentamidine synthesis of both dietary and biliary cholesterol.1, 7, 8 Overall, regulation in the intestine of cholesterol, BAs, and lipids by FGF19 and SHP may involve the combined actions of regulation of other genes that were iden

• The cytoplasmic domain of classical cadherins is highly

  2020-04-15

  

  The cytoplasmic domain of classical cadherins is highly conserved and can interact with different cytosolic proteins. Typically this domain is associated with catenin family members, including p120 catenin, β-catenin, and α-catenin, which form a cadherin-catenin complex (Fig. 1). The catenin family

• LTD and LTC cause contraction in the

  2020-04-15

  

  LTD4 and LTC4 cause contraction in the rat stomach and these contractions are sensitive to CysLT1 receptor antagonists (Goldenberg and Subers, 1983, Miura et al., 1992, Miyata et al., 1995). However, effects of other leukotrienes in the gastric contraction and inhibitory effects of potent, selective

• Experiments on the rat model

  2020-04-15

  

  Experiments on the rat model of E. coli pyelonephritis, performed to investigate the relationship between the acute inflammatory processes and the permanent kidney damage (Brooks et al., 1974), have demonstrated a positive correlation between the degree of free radical-mediated renal injury and the

15825 records 833/1055 page Previous Next First page 上5页 831832833834835 下5页 Last page