• br Materials and methods br Results and discussion The

  2018-10-25

  

  Materials and methods Results and discussion The nanoparticles of RDX and HMX were precipitated immediately on the injection of their respective solution into antisolvent (water). Stirring was continued up to a few minutes after the injection to complete the mixing to precipitate smaller parti

• El pensamiento mecanicista ir cooptando paulatinamente todas

  2018-10-25

  

  El pensamiento mecanicista irá cooptando paulatinamente todas las áreas de desarrollo humano y explicará, desde su peculiar posición, la forma en que debe funcionar la organización social y económica. Para ello era importante establecer un arquetipo de vivienda en el que la eficiencia fuera el barem

• br Para cerrar escapar del g nero Preguntarse

  2018-10-25

  

  Para cerrar: ¿escapar del género? Preguntarse si el género es un significante vacío permite considerar la importancia de pensar después el espacio semántico construido por dicho término como el lugar potencial de un desacuerdo —dado que los múltiples significados posibles están en debate constant

• JWH 073 The need for value addition in

  2018-10-25

  

  The need for value addition in tea production has become important than before to provide the consumers globally with pure Kenyan branded teas, blended at the source. Kenya exports value-added teas as tea in small packets and bags; and also herbal tea, green tea and flavored tea instead of black tea

• At the same time ABM has

  2018-10-25

  

  At the same time, ABM has also raised a good deal of criticisms. The most commonly addressed issue is that the outcome of an ABM is difficult to assess. This issue is twofold. Firstly, it involves validation of the model, i.e., knowing “whether unexpected result is a reflection of a mistake in the p

• Our in vitro and in vivo

  2018-10-24

  

  Our in vitro and in vivo studies show an increase in neurogenesis in the presence of CsA. Our findings are consistent with the idea that CsA is enhancing the survival of DG NPCs and these cells proliferate to give rise to newly born neurons. We cannot rule out the possibility that the DG contains a

• br Experimental Procedures br Author Contributions br Acknow

  2018-10-24

  

  Experimental Procedures Author Contributions Acknowledgments Introduction The reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) has revolutionized the fields of biology and medicine, providing new avenues for research and regenerative medicine applications. IPSCs a

• br Material and methods br Results

  2018-10-24

  

  Material and methods Results Discussion The role of CD146 in Tacrolimus of the adipose niche is not precisely understood. Studies analyzing its expression in human ASCs are inconsistent (Frazier et al., 2016; Mitchell et al., 2006; Pachón-Peña et al., 2011; Varma et al., 2007; Zimmerlin et

• In the present study we generated an Eva a knockout

  2018-10-24

  

  In the present study, we generated an Eva1a knockout (KO) mouse to study the physiological role of EVA1A in vivo. The analysis of Eva1a KO embryos and isolated NSCs revealed the function of EVA1A in self-renewal and neuronal differentiation of NSCs. Our study highlighted a previously unknown role of

• FUS also known as Translocated in

  2018-10-24

  

  FUS, also known as Translocated in Liposarcoma (TLS), is a DNA/RNA-binding protein containing a glycine-rich region, an RNA recognition motif and a nuclear localization signal (Lattante et al., 2013; Yang et al., 2010). In FALS, more than 50 mutations in the FUS gene have been reported (Lattante et 

• To elucidate whether the expression

  2018-10-24

  

  To elucidate whether the expression pattern of Zscan4 has any correlation with ESC proliferation, we monitored Zscan4 activity at single cell level. Also to see whether the rejuvenation factor Zscan4 correlates with the fluctuating wave of ESC pluripotency (Figure S1), we monitored Zscan4 and the pl

• br Results br Discussion We report on

  2018-10-24

  

  Results Discussion We report on the derivation and full characterization of two hESC lines (SZ-ALS1 and SZ-ALS3) with a GGGGCC expansion of approximately 270 repeats. Our C9 hESC lines were established from embryos obtained through PGD from a woman with a C9 mutation with >40 repeats in her pe

• Introduction The role of chromatin status

  2018-10-24

  

  Introduction The role of chromatin status on DNA damage response (DDR) and DNA double-strand break (DSB) repair has been extensively investigated in differentiated non-stem and cancer cells. Chromatin structure and remodeling plays an important role in the recruitment/assembly of repair factors and

• br Experimental Procedures br Author Contributions br

  2018-10-24

  

  Experimental Procedures Author Contributions Acknowledgments The work was supported by the Max Planck Society. M.D.V. is a Helmholtz Association young investigator. We thank M. Saitou (Kyoto University) and M. Boiani (MPI Muenster) for ESC lines, G. Salinas (Goettingen University) for seque

• purchase PD98059 br Results br Discussion PSC

  2018-10-24

  

  Results Discussion PSC offer great opportunities for human health, allowing the derivation of patient-specific tissues and providing disease models for drug screening. Thus, investigation of factors and mechanisms that regulate pluripotency constitutes a rapidly growing area of cutting-edge re

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