• We have based our selection scheme on classic markers that

  2018-10-29

  

  We have based our selection scheme on classic markers that have been extensively characterized and found to be exclusively expressed on only certain cell types in the mouse embryo. The stage-specific embryonic p450 inhibitors (SSEA), first described in 1978 by Solter and Knowles, are well-known hig

• br Results and discussion br Material

  2018-10-29

  

  Results and discussion Material and methods Conclusions There are various applications for cell-based therapies in cartilage repair. For knee cartilage lesion treatment, autologous chondrocyte transplantation has become the principal cell-based approach. The first human autologous chondrocy

• We aimed here to elucidate whether the effect of taurine

  2018-10-29

  

  We aimed here to elucidate whether the effect of taurine increasing proliferation occurs on stem cells as well as on neural progenitor cells. Neurospheres are formed by kinesin 5 of neural progenitor cells around one or several stem cells, but may also be formed by clusters of progenitor cells only

• br Introduction Glioblastoma is one of the deadliest among

  2018-10-26

  

  Introduction Glioblastoma is one of the deadliest among human cancers with highly dismal prognosis (Stupp et al., 2005; Tabatabai and Weller, 2011). Even with seemingly successful initial treatment, recurrence is inevitable and almost always fatal in the majority of glioblastoma cases, which impl

• additional info This has important implications for competit

  2018-10-26

  

  This has important implications for competitive transplantation experiments. Because they have the same reconstitution potential, modified HSPCs from any C57BL/6N or C57BL/6J strain can be directed compared with our CD45.1STEM strain without an additional control group. This contrasts with the situa

• br Introduction The neocortex also

  2018-10-26

  

  Introduction The neocortex, also called the dorsal cortex, is an immensely complex mammalian diazoxide Supplier structure that controls higher cognitive functions, such as problem solving and reasoning, sensory perception, emotional processing, and attention. The developing neocortex is populate

• The neurodevelopmental process is orchestrated by a series

  2018-10-26

  

  The neurodevelopmental process is orchestrated by a series of intrinsic mechanisms and extrinsic cues. Among these, intrinsic epigenetic regulation plays an important role in neural progenitor fate specification and provides one explanation about the complexity of developmental processes. DNA methyl

• Our functional analyses showed that CD

  2018-10-26

  

  Our functional analyses showed that CD38 expression inversely correlated with time of onset and persistence of the graft, confirming and extending published results obtained in xenograft models (Glimm et al., 2001; Kerre et al., 2001; Mazurier et al., 2003). Interestingly, analysis of clonal dynamic

• br Discussion br Acknowledgements This research

  2018-10-26

  

  Discussion Acknowledgements This research was supported by a grant from the Research Council of Norway (Grant no. 228664) and from Nordforsk (Grant no. 74637). The NorLAG and LOGG surveys are financed by the Research Council of Norway (Grant nos. 149564 and 168373), Ministry of Health and Care

• There are several limitations that should be considered

  2018-10-26

  

  There are several limitations that should be considered when interpreting the results of this review. First, given the search strategy, we were unable to identify unpublished studies or studies that were not published in indexed journals. Studies in languages other than English were also not include

• It seems reasonable to conclude that the Dutch who exhibit

  2018-10-26

  

  It seems reasonable to conclude that the Dutch, who exhibit an independent self-construal and are strongly individualistic, use the occasion of helping colleagues as a way to express their pride publicly and standout. This interpretation is consistent with the emotional syndrome description of North

• A chemically defined growth medium regularly used for growin

  2018-10-26

  

  A chemically-defined growth medium regularly used for growing P. pastoris was previously developed by Invitrogen Inc. (San Diego, CA, USA) and consists of basal salts, a Pichia trace metals (PTM1) solution specifically formulated for Pichia cultures and a carbon source (Invitrogen Corporation, 2002)

• We know that the cost of modafinil therapy is very

  2018-10-26

  

  We know that the cost of modafinil therapy is very superior of the one with methyphenidate. The treatment option with methylphenidate in relation with modafinil must be taken based on clinical criteria, the safety of the treatment with sympathomimetic drugs, or the associated risks for every patient

• As expected for the general adult population our study

  2018-10-26

  

  As expected for the general adult population [19], our study showed that 92% of the subjects had a monophasic pattern. The monophasic sleep pattern remains during adulthood, except in some societies that have the habit of napping after lunch [20]. Several factors could determine the ideal total slee

• In addition to the interaction between learning

  2018-10-26

  

  In addition to the interaction between learning and the circadian timekeeping system, immune function has also been found to be sensitive to daily temporal modulation. Daily physiological variations in circulating B and T 5-aminolevulinic acid [14], cell migration [15] and response of T cells to ant

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